◉    体内代谢In vivo metabolism

1）药物吸收、分布、代谢与排泄特性表征 Absorption, distribution, metabolism and excretion(ADME)

2）药物体内过程及主要药动学参数 Intracorporal process of drugs and major PK parameter

3）生物利用度Bioavailability

4）生物等效性Bioequivalence

◉    体外代谢 In vitro metabolism

1）人和动物的代谢稳定性 Species variation in metabolism

2）药物代谢相互作用 Drug-drug interactions

3）药物转运特性Drug absorption and kinetics

4）血浆蛋白结合Protein binding

5）代谢产物分析Metabolite identification, stability, and profile